Radiation Therapy in Keloids Treatment: History, Strategy, Effectiveness, and Complication
Identifieur interne : 000252 ( Main/Exploration ); précédent : 000251; suivant : 000253Radiation Therapy in Keloids Treatment: History, Strategy, Effectiveness, and Complication
Auteurs : Jing Xu [République populaire de Chine] ; Elan Yang [République populaire de Chine] ; Nan-Ze Yu [République populaire de Chine] ; Xiao Long [République populaire de Chine]Source :
- Chinese Medical Journal [ 0366-6999 ] ; 2017.
Abstract
Radiation therapy combined with surgical excision was considered as one of the most effective treatment plans for keloid lesions. However, there was no unanimity found over present literatures regarding the issue on optimized treatment strategy for keloids. We here provide a comprehensive review over this issue and emphasize on the influencing factors.
The data analyzed in this review were searched from articles included in PubMed and EMBASE databases.
The original articles and critical reviews discussing the application of radiation therapy in keloids treatment were selected for this review.
The application of radiation therapy has transitioned from simple superficial X-ray irradiation to brachytherapy. Furthermore, several factors including radiation type, dose, fraction, interval, and complications were reviewed, and the results revealed that these factors were significant toward clinical outcome at various levels.
Both past and present evidence support the idea that combination therapy of radiation and surgical therapy is safe and feasible. However, the optimization of treatment strategy was based on different radiation types and should take dose, fractions, interval, and complications into consideration, which will then decrease the rate of recurrence and increase the level of satisfaction.
Url:
DOI: 10.4103/0366-6999.209896
PubMed: 28685723
PubMed Central: 5520560
Affiliations:
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Le document en format XML
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<front><div type="abstract" xml:lang="en"><sec id="st1"><title>Objective:</title>
<p>Radiation therapy combined with surgical excision was considered as one of the most effective treatment plans for keloid lesions. However, there was no unanimity found over present literatures regarding the issue on optimized treatment strategy for keloids. We here provide a comprehensive review over this issue and emphasize on the influencing factors.</p>
</sec>
<sec id="st2"><title>Data Sources:</title>
<p>The data analyzed in this review were searched from articles included in PubMed and EMBASE databases.</p>
</sec>
<sec id="st3"><title>Study Selection:</title>
<p>The original articles and critical reviews discussing the application of radiation therapy in keloids treatment were selected for this review.</p>
</sec>
<sec id="st4"><title>Results:</title>
<p>The application of radiation therapy has transitioned from simple superficial X-ray irradiation to brachytherapy. Furthermore, several factors including radiation type, dose, fraction, interval, and complications were reviewed, and the results revealed that these factors were significant toward clinical outcome at various levels.</p>
</sec>
<sec id="st5"><title>Conclusions:</title>
<p>Both past and present evidence support the idea that combination therapy of radiation and surgical therapy is safe and feasible. However, the optimization of treatment strategy was based on different radiation types and should take dose, fractions, interval, and complications into consideration, which will then decrease the rate of recurrence and increase the level of satisfaction.</p>
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<affiliations><list><country><li>République populaire de Chine</li>
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<settlement><li>Pékin</li>
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<tree><country name="République populaire de Chine"><noRegion><name sortKey="Xu, Jing" sort="Xu, Jing" uniqKey="Xu J" first="Jing" last="Xu">Jing Xu</name>
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<name sortKey="Yu, Nan Ze" sort="Yu, Nan Ze" uniqKey="Yu N" first="Nan-Ze" last="Yu">Nan-Ze Yu</name>
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